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IR VIVO™ PRECLINICAL IMAGER

An unprecedented combination of fast acquisition speed, multicolour imaging, high spatial resolution and penetration depth allows seeing both structure and function.

Photon Etc.’s preclinical infrared imager is a multispectral infrared imaging system for in vivo studies in small animals or living organisms. IR VIVO™ offers multispectral imaging using a filter wheel and hyperspectral imaging with a continuously tunable spectral range from 850 nm to 1620 nm and a spectral resolution of < 4 nm. By virtue of high-efficiency filters and high-speed scientific grade SWIR cameras, IR VIVO™ can accurately isolate the emission of several IR labels. The imager provides the perfect tool for all applications that involve detection in the second biological window.

NIR-II IMAGING PROPERTIES

  • Non-ionizing & non-invasive
  • High spatial resolution
  • Probes for multispectral imaging
  • Intrinsic contrast
  • Functional imaging
  • High temporal resolution = Real-time dynamics

IR VIVO™

EMISSION SPECTRAL RANGE 850 – 1620 nm
Extension available in the visible up to 400 nm
FILTER TYPES   Multispectral: Filter wheel
Hyperspectral: HyperCube™
HYPERCUBE SPECTRAL RESOLUTION  < 4 nm
ILLUMINATION SOURCE 730, 780, 808 or 810 nm LEDs
Other sources available upon request
ILLUMINATION AREA 15.6 x 12.5 cm field of view for 3 mice model
FIELD OF VIEW   variable from 5 x 4 cm to 15.6 x 12.5 cm
OVERALL INSTRUMENT   DIMENSIONS   Tabletop
About 75 x 115 x 75 cm
STAGE TEMPERATURE   Up to 40ºC
ANESTHETIC TUBING AND   NOSECONE   3-mice anesthetic gas manifold supplied
COMPUTER   PC with Windows 7-64 bits included
IMAGING SOFTWARE   PHySpec™ software
SPECTRAL DATA FORMAT  HDF5, FITS
SINGLE IMAGE DATA FORMAT  HDF5, CSV, JPG, PNG, TIFF
POWER REQUIREMENT   120 VAC / 12 A / 60 Hz
ACQUISITION MODE AVAILABLE   Unfiltered (Broadband)
VIDEO MODE   Megapixel camera for sample visualization

—-  CAMERA  —-

TYPE   InGaAs (ZephIR™ 1.7)
FPA 640 x 512 pixels
PIXEL SIZE   15 µm
QE   < 75%
DYNAMIC RANGE   13/15 bit

Applications

EXAMPLES OF NIR-II IMAGING APPLICATIONS

  • Identify cancer tissue
  • Monitor blood flow & metabolic imaging
  • Monitor cell environment (pH, lipid, mRNA)
  • Monitor healing of burns & perfusion
  • Monitor heart and respiratory rates contact-free
  • Tumour imaging to guide real-time surgeries
  • Visualize microvasculature​

IDEAL FOR:

  • All in vivo applications involving detection in the second biological window
  • Drugs, toxicology, diagnostic, IR tracers and labels development studies
  • The evaluation of oxygenated versus deoxygenated blood ratios
  • Nanoparticles distribution​​

PUBLICATIONS

INSIGHT FROM THE INDUSTRY – IR VIVO
USING PRE-CLINICAL IMAGING TO DETECT CANCER

By Émilie Beaulieu-Ouellet, Application Scientist in Life Science

In this interview, Émilie Beaulieu Ouellet talks about the recently released and breakthrough imaging system: the IR VIVO™ and its technology. Photon etc.’s IR VIVO™ system is the first and only turnkey hyperspectral preclinical imager optimized for imaging in the second biological window of the near-infrared (NIR-II) / short-wavelength infrared (SWIR) range available on the market to our knowledge. NIR-II imaging will bring an unprecedented combination of fast, high resolution and penetration depth imaging at lower cost and to a broader community than current preclinical imaging techniques. Altogether, it will enable to resolve and track single biomedical targets or processes throughout small animals, thereby opening a new window of possibilities for fundamental and biopharmaceutical research.

VIDEO

Presentation of Photon etc’s Hyperspectral Microscope

From solar cells to live cell imaging, our fast and all-in-one hyperspectral microscope IMA™ offers unmatched image and data quality.

Related Products

ZEPHIR 1.7™

ZephIR™ 1.7 is an affordable scientific-grade near-infrared InGaAs camera, highly sensitive from 0.8 µm to 1.7 µm. A four-stage TE cooler, deep-cooling at -80°C, provides unrivalled low-noise levels at an astounding 200 frame-per-second rate.

HYPERCUBE

The HyperCube™ will transform your microscope, camera or a vast variety of excitation modules into a high resolution spectral imaging system, opening new research perspectives in biological imaging.